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Unique structural properties associated with mouse prion Δ105–125 protein
Murine prion protein deleted for residues 105–125 is intrinsically neurotoxic and mediates a TSE-like phenotype in transgenic mice. Equivalent and overlapping deletions were expressed in E.coli, purified and analyzed. Among mutants spanning the region 95–135, a construct lacking solely residues 105–...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Landes Bioscience
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3783109/ https://ncbi.nlm.nih.gov/pubmed/23764837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.24429 |
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