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Chip-based genotyping by mass spectrometry

Silicon chips with immobilized target DNAs were used for accurate genotyping by mass spectrometry. Genomic DNAs were amplified with PCR, and the amplified products were covalently attached to chip wells via N-succinimidyl (4-iodoacetyl)aminobenzoate (SIAB) chemistry. Primer annealing, extension, and...

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Bibliografiska uppgifter
Huvudupphovsmän: Tang, Kai, Fu, Dong-Jing, Julien, Dominique, Braun, Andreas, Cantor, Charles R., Köster, Hubert
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 1999
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC17834/
https://ncbi.nlm.nih.gov/pubmed/10468554
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