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High-throughput development and characterization of a genomewide collection of gene-based single nucleotide polymorphism markers by chip-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

We describe here a system for the rapid identification, assay development, and characterization of gene-based single nucleotide polymorphisms (SNPs). This system couples informatics tools that mine candidate SNPs from public expressed sequence tag resources and automatically designs assay reagents w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Buetow, Kenneth H., Edmonson, Michael, MacDonald, Richard, Clifford, Robert, Yip, Ping, Kelley, Jenny, Little, Daniel P., Strausberg, Robert, Koester, Hubert, Cantor, Charles R., Braun, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC14630/
https://ncbi.nlm.nih.gov/pubmed/11136232
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