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Chip-based genotyping by mass spectrometry

Silicon chips with immobilized target DNAs were used for accurate genotyping by mass spectrometry. Genomic DNAs were amplified with PCR, and the amplified products were covalently attached to chip wells via N-succinimidyl (4-iodoacetyl)aminobenzoate (SIAB) chemistry. Primer annealing, extension, and...

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Détails bibliographiques
Auteurs principaux: Tang, Kai, Fu, Dong-Jing, Julien, Dominique, Braun, Andreas, Cantor, Charles R., Köster, Hubert
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC17834/
https://ncbi.nlm.nih.gov/pubmed/10468554
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