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Chip-based genotyping by mass spectrometry

Silicon chips with immobilized target DNAs were used for accurate genotyping by mass spectrometry. Genomic DNAs were amplified with PCR, and the amplified products were covalently attached to chip wells via N-succinimidyl (4-iodoacetyl)aminobenzoate (SIAB) chemistry. Primer annealing, extension, and...

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Hlavní autoři: Tang, Kai, Fu, Dong-Jing, Julien, Dominique, Braun, Andreas, Cantor, Charles R., Köster, Hubert
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC17834/
https://ncbi.nlm.nih.gov/pubmed/10468554
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