Antigen presentation by MART-1 adenovirus-transduced interleukin-10-polarized human monocyte-derived dendritic cells

Ítems similars

• Silencing of Endogenous IL-10 in Human Dendritic Cells Leads to the Generation of an Improved CTL Response Against Human Melanoma Associated Antigenic Epitope, MART-1(27−35)
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• Knockdown of T-bet expression in Mart-1(27–35)-specific T-cell-receptor-engineered human CD4(+) CD25(−) and CD8(+) T cells attenuates effector function
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• CD4+CD25− T cells transduced to express MHC class I-restricted epitope specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model
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• Inhibition of Superoxide Generation upon TCR Engagement Rescues Mart-1(27-35) reactive T cells from Activation Induced Cell Death
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