Inhibition of Superoxide Generation upon TCR Engagement Rescues Mart-1(27-35) reactive T cells from Activation Induced Cell Death

Cytolytic T lymphocytes (CTL) undergo massive expansion upon appropriate antigenic stimulation. Homeostasis is maintained by a subsequent “contraction” of these cells. Activation-induced cell death (AICD) and programmed cell death, prevent the untoward side effects arising from excessive numbers and...

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Detalhes bibliográficos
Main Authors: Norell, Håkan, da Palma, Telma Martins, Lesher, Aaron, Kaur, Navtej, Mehrotra, Meenal, Naga, Osama S., Spivey, Natalie, Olafimihan, Seye, Chakraborty, Nitya G., Voelkel-Johnson, Christina, Nishimura, Michael I., Mukherji, Bijay, Mehrotra, Shikhar
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719828/
https://ncbi.nlm.nih.gov/pubmed/19638595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1176
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