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Proteasome substrate degradation requires association plus extended peptide
To determine the minimum requirements for substrate recognition and processing by proteasomes, the functional elements of a ubiquitin-independent degradation tag were dissected. The 37-residue C-terminus of ornithine decarboxylase (cODC) is a native degron, which also functions when appended to dive...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1782366/ https://ncbi.nlm.nih.gov/pubmed/17170706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601476 |
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