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Proteasome substrate degradation requires association plus extended peptide

To determine the minimum requirements for substrate recognition and processing by proteasomes, the functional elements of a ubiquitin-independent degradation tag were dissected. The 37-residue C-terminus of ornithine decarboxylase (cODC) is a native degron, which also functions when appended to dive...

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Detalhes bibliográficos
Main Authors: Takeuchi, Junko, Chen, Hui, Coffino, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782366/
https://ncbi.nlm.nih.gov/pubmed/17170706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601476
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