Clearance and prevention of prion infection in cell culture by anti-PrP antibodies

Prion diseases are transmissible and invariably fatal neurodegenerative disorders associated with a conformational transformation of the cellular prion protein (PrP(C)) into a self-replicating and proteinase K (PK)-resistant conformer, scrapie PrP (PrP(Sc)). Humoral immunity may significantly prolon...

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Main Authors: Pankiewicz, Joanna, Prelli, Frances, Sy, Man-Sun, Kascsak, Richard J., Kascsak, Regina B., Spinner, Daryl S., Carp, Richard I., Meeker, Harry C., Sadowski, Marcin, Wisniewski, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779824/
https://ncbi.nlm.nih.gov/pubmed/16817866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2006.04805.x
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