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Ubiquitin-dependent degradation of multiple F-box proteins by an autocatalytic mechanism

Ubiquitin-dependent degradation of regulatory proteins controls many cellular processes, including cell cycle progression, morphogenesis, and signal transduction. Skp1p-cullin-F-box protein (SCF) complexes are ubiquitin ligases composed of a core complex including Skp1p, Cdc53p, one of multiple F-bo...

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Detalhes bibliográficos
Main Authors: Galan, Jean-Marc, Peter, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17743/
https://ncbi.nlm.nih.gov/pubmed/10430906
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