A carregar...

Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation

The intracellular levels of many proteins are regulated by ubiquitin-dependent proteolysis. One of the best-characterized enzymes that catalyzes the attachment of ubiquitin to proteins is a ubiquitin ligase complex, Skp1-Cullin-F box complex containing Hrt1 (SCF). We sought to artificially target a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sakamoto, Kathleen M., Kim, Kyung B., Kumagai, Akiko, Mercurio, Frank, Crews, Craig M., Deshaies, Raymond J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC37474/
https://ncbi.nlm.nih.gov/pubmed/11438690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.141230798
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!