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HLA-DQ8 as an Ir gene in coeliac disease
DQ8 restricted gliadin peptide is immunogenic in the intestinal mucosa of HLA-DQ8 positive patients, representing the first demonstration that a given peptide may be of pathogenic significance only for a subset of coeliacs, and strongly suggests that DQ2 and DQ8 act as immune response (Ir) genes in...
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| Format: | Artigo |
| Sprache: | Inglês |
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Copyright 2003 by Gut
2003
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1773536/ https://ncbi.nlm.nih.gov/pubmed/12477747 |
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