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The production and crystallization of the human leukocyte antigen class II molecules HLA-DQ2 and HLA-DQ8 complexed with deamidated gliadin peptides implicated in coeliac disease

The major histocompatibility complex (MHC) class II molecules HLA-DQ2 and HLA-DQ8 are key risk factors in coeliac disease, as they bind deamidated gluten peptides that are subsequently recognized by CD4(+) T cells. Here, the production and crystallization of both HLA-DQ2 and HLA-DQ8 in complex with...

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Detaylı Bibliyografya
Asıl Yazarlar: Henderson, Kate N., Reid, Hugh H., Borg, Natalie A., Broughton, Sophie E., Huyton, Trevor, Anderson, Robert P., McCluskey, James, Rossjohn, Jamie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: International Union of Crystallography 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2344093/
https://ncbi.nlm.nih.gov/pubmed/18084083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107051408
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