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The production and crystallization of the human leukocyte antigen class II molecules HLA-DQ2 and HLA-DQ8 complexed with deamidated gliadin peptides implicated in coeliac disease
The major histocompatibility complex (MHC) class II molecules HLA-DQ2 and HLA-DQ8 are key risk factors in coeliac disease, as they bind deamidated gluten peptides that are subsequently recognized by CD4(+) T cells. Here, the production and crystallization of both HLA-DQ2 and HLA-DQ8 in complex with...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2344093/ https://ncbi.nlm.nih.gov/pubmed/18084083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107051408 |
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