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Survival of adult neurons lacking cholesterol synthesis in vivo

BACKGROUND: Cholesterol, an essential component of all mammalian plasma membranes, is highly enriched in the brain. Both during development and in the adult, brain cholesterol is derived from local cholesterol synthesis and not taken up from the circulation. However, the contribution of neurons and...

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Detalhes bibliográficos
Main Authors: Fünfschilling, Ursula, Saher, Gesine, Xiao, Le, Möbius, Wiebke, Nave, Klaus-Armin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1769390/
https://ncbi.nlm.nih.gov/pubmed/17199885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-8-1
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