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Survival of adult neurons lacking cholesterol synthesis in vivo

BACKGROUND: Cholesterol, an essential component of all mammalian plasma membranes, is highly enriched in the brain. Both during development and in the adult, brain cholesterol is derived from local cholesterol synthesis and not taken up from the circulation. However, the contribution of neurons and...

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Библиографические подробности
Главные авторы: Fünfschilling, Ursula, Saher, Gesine, Xiao, Le, Möbius, Wiebke, Nave, Klaus-Armin
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1769390/
https://ncbi.nlm.nih.gov/pubmed/17199885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-8-1
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