Neurod1 is essential for the survival and maturation of adult-born neurons

The transcriptional program that controls adult neurogenesis is unknown. We generated mice with an inducible stem cell–specific deletion of Neurod1, resulting in substantially fewer newborn neurons in the hippocampus and olfactory bulb. Thus, Neurod1 is cell-intrinsically required for the survival a...

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Bibliographic Details
Main Authors: Gao, Zhengliang, Ure, Kerstin, Ables, Jessica L, Lagace, Diane C, Nave, Klaus-Armin, Goebbels, Sandra, Eisch, Amelia J, Hsieh, Jenny
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365543/
https://ncbi.nlm.nih.gov/pubmed/19701197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2385
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