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Cdk5 is essential for adult hippocampal neurogenesis

The molecular factors regulating adult neurogenesis must be understood to harness the therapeutic potential of neuronal stem cells. Although cyclin-dependent kinase 5 (Cdk5) plays a critical role in embryonic corticogenesis, its function in adult neurogenesis is unknown. Here, we assessed the role o...

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Hlavní autoři: Lagace, Diane C., Benavides, David R., Kansy, Janice W., Mapelli, Marina, Greengard, Paul, Bibb, James A., Eisch, Amelia J.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587597/
https://ncbi.nlm.nih.gov/pubmed/19017796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810137105
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