Dietary cholesterol promotes repair of demyelinated lesions in the adult brain

Multiple Sclerosis (MS) is an inflammatory demyelinating disorder in which remyelination failure contributes to persistent disability. Cholesterol is rate-limiting for myelin biogenesis in the developing CNS; however, whether cholesterol insufficiency contributes to remyelination failure in MS, is u...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Berghoff, Stefan A., Gerndt, Nina, Winchenbach, Jan, Stumpf, Sina K., Hosang, Leon, Odoardi, Francesca, Ruhwedel, Torben, Böhler, Carolin, Barrette, Benoit, Stassart, Ruth, Liebetanz, David, Dibaj, Payam, Möbius, Wiebke, Edgar, Julia M., Saher, Gesine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5286209/
https://ncbi.nlm.nih.gov/pubmed/28117328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14241
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