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Cholesterol Regulates the Endoplasmic Reticulum Exit of the Major Membrane Protein P0 Required for Peripheral Myelin Compaction

Rapid impulse conduction requires electrical insulation of axons by myelin, a cholesterol-rich extension of the glial cell membrane with a characteristic composition of proteins and lipids. Mutations in several myelin protein genes cause endoplasmic reticulum (ER) retention and disease, presumably a...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Saher, Gesine, Quintes, Susanne, Möbius, Wiebke, Wehr, Michael C., Krämer-Albers, Eva-Maria, Brügger, Britta, Nave, Klaus-Armin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6665514/
https://ncbi.nlm.nih.gov/pubmed/19439587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0686-09.2009
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