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Precise physical models of protein–DNA interaction from high-throughput data

A cell's ability to regulate gene transcription depends in large part on the energy with which transcription factors (TFs) bind their DNA regulatory sites. Obtaining accurate models of this binding energy is therefore an important goal for quantitative biology. In this article, we present a pri...

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Detalles Bibliográficos
Autores principales: Kinney, Justin B., Tkačik, Gašper, Callan, Curtis G.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1766414/
https://ncbi.nlm.nih.gov/pubmed/17197415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609908104
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