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Making the most of high-throughput protein-interaction data

We review the estimation of coverage and error rate in high-throughput protein-protein interaction datasets and argue that reports of the low quality of such data are to a substantial extent based on misinterpretations. Probabilistic statistical models and methods can be used to estimate properties...

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Detalhes bibliográficos
Main Authors: Gentleman, Robert, Huber, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2246275/
https://ncbi.nlm.nih.gov/pubmed/18001486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-10-112
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