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Coverage and error models of protein-protein interaction data by directed graph analysis

Using a directed graph model for bait to prey systems and a multinomial error model, we assessed the error statistics in all published large-scale datasets for Saccharomyces cerevisiae and characterized them by three traits: the set of tested interactions, artifacts that lead to false-positive or fa...

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Autores principales: Chiang, Tony, Scholtens, Denise, Sarkar, Deepayan, Gentleman, Robert, Huber, Wolfgang
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375024/
https://ncbi.nlm.nih.gov/pubmed/17845715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-9-r186
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