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Precise physical models of protein–DNA interaction from high-throughput data

A cell's ability to regulate gene transcription depends in large part on the energy with which transcription factors (TFs) bind their DNA regulatory sites. Obtaining accurate models of this binding energy is therefore an important goal for quantitative biology. In this article, we present a pri...

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Detalhes bibliográficos
Main Authors: Kinney, Justin B., Tkačik, Gašper, Callan, Curtis G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1766414/
https://ncbi.nlm.nih.gov/pubmed/17197415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609908104
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