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Precise physical models of protein–DNA interaction from high-throughput data

A cell's ability to regulate gene transcription depends in large part on the energy with which transcription factors (TFs) bind their DNA regulatory sites. Obtaining accurate models of this binding energy is therefore an important goal for quantitative biology. In this article, we present a pri...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kinney, Justin B., Tkačik, Gašper, Callan, Curtis G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1766414/
https://ncbi.nlm.nih.gov/pubmed/17197415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609908104
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