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Precise physical models of protein–DNA interaction from high-throughput data

A cell's ability to regulate gene transcription depends in large part on the energy with which transcription factors (TFs) bind their DNA regulatory sites. Obtaining accurate models of this binding energy is therefore an important goal for quantitative biology. In this article, we present a pri...

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Autors principals: Kinney, Justin B., Tkačik, Gašper, Callan, Curtis G.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1766414/
https://ncbi.nlm.nih.gov/pubmed/17197415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609908104
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