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High-throughput characterization of protein–protein interactions by reprogramming yeast mating

High-throughput methods for screening protein–protein interactions enable the rapid characterization of engineered binding proteins and interaction networks. While existing approaches are powerful, none allow quantitative library-on-library characterization of protein interactions in a modifiable ex...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Younger, David, Berger, Stephanie, Baker, David, Klavins, Eric
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699035/
https://ncbi.nlm.nih.gov/pubmed/29087945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705867114
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