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Multiple pathways contribute to the pathogenesis of Huntington disease
Huntington disease (HD) is caused by expansion of a polyglutamine (polyQ) domain in the protein known as huntingtin (htt), and the disease is characterized by selective neurodegeneration. Expansion of the polyQ domain is not exclusive to HD, but occurs in eight other inherited neurodegenerative diso...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BioMed Central
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1764744/ https://ncbi.nlm.nih.gov/pubmed/17173700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-1-19 |
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