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The Triphosphate of β-D-4’-C-Ethynyl-2’,3’-Dideoxycytidine is the Preferred Enantiomer Substrate for HIV Reverse Transcriptase

The enantioselective synthesis of the β-D (1) enantiomer of 4’-C-ethynyl-2’,3’-dideoxycytidine confirms an earlier stereochemical assignment that was strictly based on the ability of HIV reverse transcriptase and its M184V mutant to discriminate between the D- and L-configuration of nucleoside 5’-tr...

詳細記述

保存先:
書誌詳細
主要な著者: Siddiqui, Maqbool A., Marquez, Victor E.
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1764207/
https://ncbi.nlm.nih.gov/pubmed/17046266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2006.09.061
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