The tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle control

Alteration of the FHIT (fragile histidine triad) gene occurs as an early and frequent event in lung carcinogenesis. FHIT gene transfer into lung cancer cell line H460 lacking Fhit protein expression resulted in reversion of tumorigenicity. To gain insight into the biological function of FHIT, we com...

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書誌詳細

出版年:	Proc Natl Acad Sci U S A
主要な著者:	Sard, Laura, Accornero, Paola, Tornielli, Silvana, Delia, Domenico, Bunone, Giuseppe, Campiglio, Manuela, Colombo, Mario P., Gramegna, Marcella, Croce, Carlo M., Pierotti, Marco A., Sozzi, Gabriella
フォーマット:	Artigo
言語:	Inglês
出版事項:	National Academy of Sciences 1999
主題:	Biological Sciences
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17543/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10411902/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.15.8489
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