Helicobacter pylori cytotoxin: importance of native conformation for induction of neutralizing antibodies.

We have attempted to express the Helicobacter pylori vacuolating cytotoxin in Escherichia coli. Although the 95-kDa VacA polypeptide was expressed abundantly, it completely lacked any biological activity. In addition, this material failed to induce neutralizing antibodies after immunization of rabbi...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Manetti, R, Massari, P, Burroni, D, de Bernard, M, Marchini, A, Olivieri, R, Papini, E, Montecucco, C, Rappuoli, R, Telford, J L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173637/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7591088/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.11.4476-4480.1995
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!