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Identification of the Helicobacter pylori VacA Toxin Domain Active in the Cell Cytosol

Cells exposed to Helicobacter pylori toxin VacA develop large vacuoles which originate from massive swelling of membranous compartments at late stages of the endocytic pathway. When expressed in the cytosol, VacA induces vacuolization as it does when added from outside. This and other evidence indic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: de Bernard, Marina, Burroni, Daniela, Papini, Emanuele, Rappuoli, Rino, Telford, John, Montecucco, Cesare
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC108763/
https://ncbi.nlm.nih.gov/pubmed/9826387
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