Identification of the Helicobacter pylori VacA Toxin Domain Active in the Cell Cytosol

Cells exposed to Helicobacter pylori toxin VacA develop large vacuoles which originate from massive swelling of membranous compartments at late stages of the endocytic pathway. When expressed in the cytosol, VacA induces vacuolization as it does when added from outside. This and other evidence indic...

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Hlavní autoři: de Bernard, Marina, Burroni, Daniela, Papini, Emanuele, Rappuoli, Rino, Telford, John, Montecucco, Cesare
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
Témata:
Molecular and Cellular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC108763/
https://ncbi.nlm.nih.gov/pubmed/9826387
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