Carboxy-Terminal Proteolytic Processing of Helicobacter pylori Vacuolating Toxin

The vacA gene of Helicobacter pylori strain 60190 encodes a 1,287-amino-acid protoxin, which undergoes cleavage of a 33-amino-acid amino-terminal signal sequence and carboxy-terminal proteolytic processing to yield a mature secreted toxin. Several features of VacA suggest that it belongs to the auto...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Nguyen, Viet Q., Caprioli, Richard M., Cover, Timothy L.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Molecular Pathogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97915/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11119549/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.1.543-546.2001
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