Amino-Terminal Hydrophobic Region of Helicobacter pylori Vacuolating Cytotoxin (VacA) Mediates Transmembrane Protein Dimerization

Helicobacter pylori VacA is a secreted protein toxin that forms channels in lipid bilayers and induces multiple structural and functional alterations in eukaryotic cells. A unique hydrophobic segment at the amino terminus of VacA contains three tandem repeats of a GxxxG motif that is characteristic...

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Bibliografiske detaljer
Main Authors: McClain, Mark S., Cao, Ping, Cover, Timothy L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC98002/
https://ncbi.nlm.nih.gov/pubmed/11160018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.2.1181-1184.2001
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