Plasma Membrane Cholesterol Modulates Cellular Vacuolation Induced by the Helicobacter pylori Vacuolating Cytotoxin

The Helicobacter pylori vacuolating cytotoxin (VacA) induces the degenerative vacuolation of mammalian cells both in vitro and in vivo. Here, we demonstrate that plasma membrane cholesterol is essential for vacuolation of mammalian cells by VacA. Vacuole biogenesis in multiple cell lines was complet...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Patel, Hetal K., Willhite, David C., Patel, Rakhi M., Ye, Dan, Williams, Christopher L., Torres, Eric M., Marty, Kent B., MacDonald, Robert A., Blanke, Steven R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2002
Pynciau:
Molecular Pathogenesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC128184/
https://ncbi.nlm.nih.gov/pubmed/12117919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4112-4123.2002
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg