Plasma Membrane Cholesterol Modulates Cellular Vacuolation Induced by the Helicobacter pylori Vacuolating Cytotoxin

The Helicobacter pylori vacuolating cytotoxin (VacA) induces the degenerative vacuolation of mammalian cells both in vitro and in vivo. Here, we demonstrate that plasma membrane cholesterol is essential for vacuolation of mammalian cells by VacA. Vacuole biogenesis in multiple cell lines was complet...

詳細記述

保存先:
書誌詳細
主要な著者: Patel, Hetal K., Willhite, David C., Patel, Rakhi M., Ye, Dan, Williams, Christopher L., Torres, Eric M., Marty, Kent B., MacDonald, Robert A., Blanke, Steven R.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2002
主題:
Molecular Pathogenesis
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC128184/
https://ncbi.nlm.nih.gov/pubmed/12117919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4112-4123.2002
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