Plasma Membrane Cholesterol Modulates Cellular Vacuolation Induced by the Helicobacter pylori Vacuolating Cytotoxin

The Helicobacter pylori vacuolating cytotoxin (VacA) induces the degenerative vacuolation of mammalian cells both in vitro and in vivo. Here, we demonstrate that plasma membrane cholesterol is essential for vacuolation of mammalian cells by VacA. Vacuole biogenesis in multiple cell lines was complet...

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Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Patel, Hetal K., Willhite, David C., Patel, Rakhi M., Ye, Dan, Williams, Christopher L., Torres, Eric M., Marty, Kent B., MacDonald, Robert A., Blanke, Steven R.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2002
Matèries:	Molecular Pathogenesis
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128184/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12117919/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.8.4112-4123.2002
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