Amino-Terminal Hydrophobic Region of Helicobacter pylori Vacuolating Cytotoxin (VacA) Mediates Transmembrane Protein Dimerization

Helicobacter pylori VacA is a secreted protein toxin that forms channels in lipid bilayers and induces multiple structural and functional alterations in eukaryotic cells. A unique hydrophobic segment at the amino terminus of VacA contains three tandem repeats of a GxxxG motif that is characteristic...

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Εκδόθηκε σε:	Infect Immun
Κύριοι συγγραφείς:	McClain, Mark S., Cao, Ping, Cover, Timothy L.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Microbiology (ASM) 2001
Θέματα:	Molecular Pathogenesis
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98002/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160018/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.2.1181-1184.2001
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