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Carboxy-Terminal Proteolytic Processing of Helicobacter pylori Vacuolating Toxin

The vacA gene of Helicobacter pylori strain 60190 encodes a 1,287-amino-acid protoxin, which undergoes cleavage of a 33-amino-acid amino-terminal signal sequence and carboxy-terminal proteolytic processing to yield a mature secreted toxin. Several features of VacA suggest that it belongs to the auto...

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Detalles Bibliográficos
Main Authors: Nguyen, Viet Q., Caprioli, Richard M., Cover, Timothy L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC97915/
https://ncbi.nlm.nih.gov/pubmed/11119549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.1.543-546.2001
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