Helicobacter pylori cytotoxin: importance of native conformation for induction of neutralizing antibodies.
We have attempted to express the Helicobacter pylori vacuolating cytotoxin in Escherichia coli. Although the 95-kDa VacA polypeptide was expressed abundantly, it completely lacked any biological activity. In addition, this material failed to induce neutralizing antibodies after immunization of rabbi...
محفوظ في:
| الحاوية / القاعدة: | Infect Immun |
|---|---|
| المؤلفون الرئيسيون: | , , , , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Microbiology (ASM)
1995
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173637/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7591088/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.11.4476-4480.1995 |
| الوسوم: |
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