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Intracellular antibody-caspase-mediated cell killing: An approach for application in cancer therapy

Antibodies have been expressed inside cells in an attempt to ablate the function of oncogene products. To make intracellular antibodies more generally applicable and effective in cancer therapy, we have devised a method in which programmed cell death or apoptosis can be triggered by specific antibod...

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Bibliografiske detaljer
Main Authors: Tse, Eric, Rabbitts, Terence H.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC17330/
https://ncbi.nlm.nih.gov/pubmed/11050246
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