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Combination of Antibody Targeting and PTD-Mediated Intracellular Toxin Delivery for Colorectal Cancer Therapy

The bottlenecks of current chemotherapy in the treatment of colorectal cancer lie in the ineffectiveness of the existing anti-cancer small molecule drugs as well as the dose-limiting toxicity caused by the nonselective action on normal tissues by such drugs. To address these problems, we introduce a...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Shin, Meong Cheol, Zhang, Jian, Ah Min, Kyoung, Lee, Kyuri, Moon, Cheol, Balthasar, Joseph P., Yang, Victor C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252800/
https://ncbi.nlm.nih.gov/pubmed/25204286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.08.030
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