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Selection of antibodies for intracellular function using a two-hybrid in vivo system

Expression of antibodies inside cells has been used successfully to ablate protein function. This finding suggests that the technology should have an impact on disease treatment and in functional genomics where proteins of unknown function are predicted from genomic sequences. A major hindrance is t...

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Autori principali: Visintin, Michela, Tse, Eric, Axelson, Hakan, Rabbitts, Terence H., Cattaneo, Antonino
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC18353/
https://ncbi.nlm.nih.gov/pubmed/10518517
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