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Targeted cell killing by reconstituted caspases

We have developed a two-component system involving reconstituted caspase (recCaspase) for selective and/or conditional ablation of targeted cells. Caspases, the executioners of programmed cell death, are normally synthesized as inactive zymogens and are activated by proteolytic processing of their s...

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Autors principals: Chelur, Dattananda S., Chalfie, Martin
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892955/
https://ncbi.nlm.nih.gov/pubmed/17283333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610877104
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