Use of in vitro topoisomerase II assays for studying quinolone antibacterial agents.

Several quinolones and antitumor compounds were tested as inhibitors of purified calf thymus topoisomerase II in unknotting, catenation, radiolabeled DNA cleavage, and quantitative nonradiolabeled cleavage assays. The antitumor agents VP-16 (demethylepipodophyllotoxin ethylio-beta-D-glucoside) and e...

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Bibliografski detalji

Izdano u:	Antimicrob Agents Chemother
Glavni autori:	Barrett, J F, Gootz, T D, McGuirk, P R, Farrell, C A, Sokolowski, S A
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1989
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2556075/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.10.1697
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