Use of in vitro topoisomerase II assays for studying quinolone antibacterial agents.

Several quinolones and antitumor compounds were tested as inhibitors of purified calf thymus topoisomerase II in unknotting, catenation, radiolabeled DNA cleavage, and quantitative nonradiolabeled cleavage assays. The antitumor agents VP-16 (demethylepipodophyllotoxin ethylio-beta-D-glucoside) and e...

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Argitaratua izan da:	Antimicrob Agents Chemother
Egile Nagusiak:	Barrett, J F, Gootz, T D, McGuirk, P R, Farrell, C A, Sokolowski, S A
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 1989
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2556075/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.10.1697
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