Use of in vitro topoisomerase II assays for studying quinolone antibacterial agents.

Several quinolones and antitumor compounds were tested as inhibitors of purified calf thymus topoisomerase II in unknotting, catenation, radiolabeled DNA cleavage, and quantitative nonradiolabeled cleavage assays. The antitumor agents VP-16 (demethylepipodophyllotoxin ethylio-beta-D-glucoside) and e...

Descripció completa

Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Barrett, J F, Gootz, T D, McGuirk, P R, Farrell, C A, Sokolowski, S A
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1989
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2556075/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.10.1697
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!