Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles

Melanin, the pigment in hair, skin, eyes, and feathers, protects external tissue from damage by UV light. In contrast, neuromelanin (NM) is found in deep brain regions, specifically in loci that degenerate in Parkinson's disease. Although this distribution suggests a role for NM in Parkinson�...

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Detalhes bibliográficos
Main Authors: Sulzer, David, Bogulavsky, Johanna, Larsen, Kristin E., Behr, Gerald, Karatekin, Erdem, Kleinman, Mark H., Turro, Nicholas, Krantz, David, Edwards, Robert H., Greene, Lloyd A., Zecca, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Physical Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17261/
https://ncbi.nlm.nih.gov/pubmed/11050221
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