α-Synuclein Overexpression Increases Cytosolic Catecholamine Concentration

Dysregulation of dopamine homeostasis and elevation of the cytosolic level of the transmitter have been suggested to underlie the vulnerability of catecholaminergic neurons in Parkinson’s disease. Because several known mutations in α-synuclein or overexpression of the wild-type (WT) protein causes f...

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Publicado no:J Neurosci
Main Authors: Mosharov, Eugene V., Staal, Roland G. W., Bové, Jordi, Prou, Delphine, Hananiya, Anthonia, Markov, Dmitriy, Poulsen, Nathan, Larsen, Kristin E., Moore, Candace M. H., Troyer, Matthew D., Edwards, Robert H., Przedborski, Serge, Sulzer, David
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674515/
https://ncbi.nlm.nih.gov/pubmed/16957086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0519-06.2006
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