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α-Synuclein Overexpression Increases Cytosolic Catecholamine Concentration

Dysregulation of dopamine homeostasis and elevation of the cytosolic level of the transmitter have been suggested to underlie the vulnerability of catecholaminergic neurons in Parkinson’s disease. Because several known mutations in α-synuclein or overexpression of the wild-type (WT) protein causes f...

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Publicat a:J Neurosci
Autors principals: Mosharov, Eugene V., Staal, Roland G. W., Bové, Jordi, Prou, Delphine, Hananiya, Anthonia, Markov, Dmitriy, Poulsen, Nathan, Larsen, Kristin E., Moore, Candace M. H., Troyer, Matthew D., Edwards, Robert H., Przedborski, Serge, Sulzer, David
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674515/
https://ncbi.nlm.nih.gov/pubmed/16957086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0519-06.2006
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