Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles

Melanin, the pigment in hair, skin, eyes, and feathers, protects external tissue from damage by UV light. In contrast, neuromelanin (NM) is found in deep brain regions, specifically in loci that degenerate in Parkinson's disease. Although this distribution suggests a role for NM in Parkinson�...

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Détails bibliographiques
Auteurs principaux: Sulzer, David, Bogulavsky, Johanna, Larsen, Kristin E., Behr, Gerald, Karatekin, Erdem, Kleinman, Mark H., Turro, Nicholas, Krantz, David, Edwards, Robert H., Greene, Lloyd A., Zecca, Luigi
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2000
Sujets:
Physical Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC17261/
https://ncbi.nlm.nih.gov/pubmed/11050221
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