Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles

Melanin, the pigment in hair, skin, eyes, and feathers, protects external tissue from damage by UV light. In contrast, neuromelanin (NM) is found in deep brain regions, specifically in loci that degenerate in Parkinson's disease. Although this distribution suggests a role for NM in Parkinson�...

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Autori principali: Sulzer, David, Bogulavsky, Johanna, Larsen, Kristin E., Behr, Gerald, Karatekin, Erdem, Kleinman, Mark H., Turro, Nicholas, Krantz, David, Edwards, Robert H., Greene, Lloyd A., Zecca, Luigi
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2000
Soggetti:
Physical Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC17261/
https://ncbi.nlm.nih.gov/pubmed/11050221
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