Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles

Melanin, the pigment in hair, skin, eyes, and feathers, protects external tissue from damage by UV light. In contrast, neuromelanin (NM) is found in deep brain regions, specifically in loci that degenerate in Parkinson's disease. Although this distribution suggests a role for NM in Parkinson�...

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Bibliografiska uppgifter
Huvudupphovsmän: Sulzer, David, Bogulavsky, Johanna, Larsen, Kristin E., Behr, Gerald, Karatekin, Erdem, Kleinman, Mark H., Turro, Nicholas, Krantz, David, Edwards, Robert H., Greene, Lloyd A., Zecca, Luigi
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2000
Ämnen:
Physical Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC17261/
https://ncbi.nlm.nih.gov/pubmed/11050221
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