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Ultrastructural alterations induced by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi.

We report the ultrastructural alterations induced during the proliferative stages of Trypanosoma (Schizotrypanum) cruzi, the causative agent of Chagas' disease, by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, which had previously been shown to be potent growth inhibitors who...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Lazardi, K, Urbina, J A, de Souza, W
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1990
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC172006/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2073100/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.11.2097
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